Stem Cell Therapies for Spinal Cord Injury in Humans: A Review of Recent Clinical Research
Recently, cell transplantation has emerged as a promising treatment for spinal cord injury (SCI). Over the past decade, numerous clinical studies of SCI have been conducted using various types of cells, including fetal neural stem/progenitor cells (NS/PCs), pluripotent stem cell-derived NS/PCs, mesenchymal stem/stromal cells (MSCs), olfactory ensheathing cells, and Schwann cells. Promising results have been reported for patients with subacute SCI, especially in studies involving MSCs, such as those conducted with Stemirac, although no universally recognized breakthroughs have been achieved. Allogenic NS/PCs may offer advantages over autologous MSCs because they have the potential for cell engraftment within the spinal cord and can be prepared in advance, facilitating their administration during the hyperacute phase.
Quadriceps and hamstring muscles strength differences in adolescent and adult recreational athletes 6 months after autograft bone-patellar-tendon-bone anterior cruciate ligament reconstruction: A retrospective study
Knee muscle strength recovery after anterior cruciate ligament reconstruction (ACLR) is crucial for a safe return to sport (RTS) but it is poorly described in the adolescent population. Therefore, we compared the knee muscle strength at 6 months post-surgery in adults and adolescents. We hypothesized a greater muscular strength in adolescents 6 months after ACLR.
Benefits and limitations of diagnostic shoulder arthroscopy for painful anatomical shoulder arthroplasty investigation
Shoulder arthroscopy is a valuable diagnostic tool for painful anatomical shoulder arthroplasty offering some therapeutic opportunities. It has been demonstrated as a sensitive option to diagnose periprosthetic joint infection and is most frequently used for this purpose. Additionally, it offers the possibility of diagnosing some complications after shoulder arthroplasty such as component loosening or rotator cuff failure. As therapeutic options are mostly limited to arthrolysis, and débridement and decompression, most patients will have to face a revision arthroplasty. Nevertheless, diagnostic arthroscopy provides a valuable tool to gain information on the cause of the symptoms to determine further steps of treatment.
Chlorhexidine irrigation during TSA may decrease rates of positive deep C. acnes cultures
Patients who received subcutaneous 0.05% chlorhexidine gluconate antisepsis during primary total shoulder arthroplasty had a significantly decreased rate of positive deep cultures of Cutibacterium acnes, according to a study.
10 types of exercise to try with arthritis of the knee
Exercises for knee arthritis, such as leg lifts, can strengthen the muscles around the knee joint and help a person stay active. Swimming and elliptical training are also suitable options.
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