Clinical Application of Mesenchymal Stem Cells in Orthopaedics and Traumatology in Daily Practice
Mesenchymal stem cells (MSCs) have been widely used in preclinical and clinical orthopaedic and traumatology studies (1). Compared to other cell therapies, MSCs have a variety of characteristics, such as a lower risk of teratoma than pluripotent stem cells, stemness potency, targeted therapy through chemo-attraction, ease of isolation, and rapid proliferation (2). However, the application from bench to bedside requires a standardized procedure for its administration (1).
Source: ScienceDirect
Short-Term Clinical Outcomes of Platelet-Rich Plasma Injections in Patients With Rotator Cuff Tendinopathy and Partial-Thickness Rotator Cuff Tears
Platelet-rich plasma (PRP) has been increasingly applied for rotator cuff pathology; however, clinical evidence regarding its short-term efficacy remains limited. This study evaluated the effectiveness of a single PRP injection for rotator cuff injury.
Source: Cureus
Arthroscopic repair of posterosuperior massive rotator cuff tears provides good clinical outcomes despite high re-tear rate in the mid-term
Arthroscopic repair of posterosuperior MRCT provides significant pain and function improvement. Despite a high retear rate, mid-term clinical results remain favorable, with low complication and revision rates.
Source: JSES International
Platelet-Rich Plasma in the Treatment of Knee Osteoarthritis: A Bibliometric Analysis of Global Research Trends
Knee osteoarthritis (OA) represents a major cause of pain and disability among older adults. Platelet-rich plasma (PRP) has emerged as a promising biologic therapy aimed at modulating inflammation and promoting cartilage repair. As the clinical use of PRP has expanded, a rapidly growing body of literature has developed examining its efficacy and mechanisms of action in knee OA. Bibliometric analysis provides a useful method to evaluate research productivity, collaborative networks, and emerging trends within a scientific field.
Source: Orthopedic Reviews
Research moves closer to `smart` sensors in knee replacements
If you have a knee replacement, imagine pointing your phone at your knee and pulling up an app that tells you how much stress the artificial joint is experiencing. Knowing the activities that cause the biggest problems-which can lead to a second replacement surgery-would be invaluable. Research led by Binghamton University is closer to making this technology a reality.
Source: Medical Xpress
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