Safety and Efficacy of Mesenchymal Stem Cell Therapy in Aging Frailty: A Systematic Review
Aging frailty is a multifactorial geriatric syndrome characterized by reduced physiological reserve across multiple interrelated systems, leading to increased vulnerability to adverse health outcomes. Mesenchymal stem cells (MSCs) have emerged as a potential therapeutic intervention due to their immunomodulatory and regenerative properties. This systematic review aimed to evaluate the available clinical evidence regarding the safety and efficacy of MSC administration in individuals with aging frailty.
Source: MDPI
Association Between Preoperative Platelet-Rich Plasma Injection Timing and Infection Risk Following Total Knee Arthroplasty
Our study demonstrated that in patients who received PRP injections prior to TKA, injection timing was not associated with increased risk of prosthetic joint infection. A numerically higher rate of 2-year superficial surgical site infection was observed among patients receiving PRP within 6 months of surgery; however, this finding did not meet the predefined threshold for statistical significance and was based on limited event counts.
Source: ScienceDirect
Traumatic Serratus Anterior Muscle Tear Presenting as Isolated Posterior Shoulder Pain in a Professional Volleyball Athlete: A Case Report
Serratus anterior muscle injuries are rare, most commonly reported in rowing and overhead throwing athletes. These injuries typically present with anterolateral chest wall pain and a palpable mass. Atypical presentations may lead to diagnostic challenges, particularly when symptoms mimic shoulder pathology. We report the case of a 26-year-old male professional volleyball player who presented with acute-onset posterior shoulder pain following a serving motion.
Source: Cureus
Biologic Therapies for Knee Osteoarthritis: A Structured Narrative Review of Joint Preservation Strategies and Clinical Outcomes
As interest in joint preservation strategies has grown, biologic therapies have emerged as promising approaches capable of modulating the intra-articular environment and potentially delaying invasive interventions.
Source: Arthroplasty Today
6 Joints You Probably Didn`t Know Could Be Replaced
You probably have a friend or relative who’s gotten a new hip or knee replacement. Maybe you’ve even heard about someone who is getting their shoulder replaced. But advances in orthopedic surgery now make it possible to replace some of the body’s smaller and more complex joints, including ankles, elbows, thumbs and finger joints.
Source: Right As Rain - UW Medicine
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